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Nitric oxide (NO) has been recognized as one of the most valuable highly reactive signaling molecules with numerous roles in human health, including blood flow and vascular tone

Pflugers Arch 442:28696 Sato H, Shiiya A, Kimata M, Maebara K, Tamba M, Sakakura Y, Makino N, Sugiyama F, Yagami K, Moriguchi T, Takahashi S, Bannai S (2005) Redox imbalance in cystine/glutamate transporter-deficient mice

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Despite the low doses used, a significant benefit was observed