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Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono) // Diabetes Care

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A retrospective, population-based cohort study found that treatment with glucagon-like peptide-1 (GLP-1) receptor agonists was safe and associated with lower risks of cardiovascular or psychiatric comorbidities and lower mortality among patients with psoriasis

As orlistat works by reducing the amount of fat absorbed in the gut, consuming high amounts of fat while on this medication may lead to worse side effects

The mechanism of action is the same as GLP-1, including stimulation of insulin secretion, slowing gastric emptying, and reducing postprandial glucagon secretion in a glucose-dependent fashion