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It is not by chance that the most recent clinical guidelines [10] continue to advocate the use of antidiabetic drugs that have been proven to reduce cardiovascular events and mortality

Abbreviations APAP : Acetaminophen GJ : Gap-junction NAC : N-acetylcysteine GSH : Glutathione NAPQI : N-acetyl-p-benzoquinone imine ROS : Reactive oxygen species Nrf2 : Nuclear factor E2-related factor 2 Cx32 : Connexin 32 TTSP : Type II transmembrane serine protease HGF : Hepatocyte growth factor References Chiew AL, Isbister GK