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NAD + also enhances mitochondrial suppression of oxygen and ATP production

Sasaki S, Drummen GPC, Konishi G (2016) Recent advances in twisted intramolecular charge transfer (TICT) fluorescence and related phenomena in materials chemistry

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Initially observed in toxicology, where sub-toxic doses of certain chemicals paradoxically improved organismal function, the term hormesis was later coined to describe this broadly applicable phenomenon, encompassing cellular, molecular, and organismal levels

This depends on a patients frequency of intake and metabolism