Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study
The mechanisms underlying an augmented GLP-1 response to intraduodenal glucose after Met (60 min) and Met (30 min) remain uncertain, but may reflect an effect of metformin on inhibiting glucose absorption in the upper small intestine, with consequent increased exposure of L cells to glucose more distally in the gut
Cold Spring Harbor Symposia on Quantitative Biology , 72, 579597
A lot of people dont bring up diarrhea on GLP-1 medications because they feel its awkward or think its just part of it. I make a point to ask, because bowel changes can signal dehydration, food triggers, or that the dose is moving too fast
The peptide cannot repair tissue faster than ongoing damage accumulates