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Furthermore, BPC-157 stabilizes existing vascular structures and modulates vascular tone via NO-mediated vasodilation, thereby safeguarding tissues against ischemic damage during repair processes [20, 24, 41]
Additional class-related concerns include: Gallbladder disease , including cholelithiasis (gallstones) and cholecystitis, as observed with GLP-1 receptor agonist medicines [27] Dehydration and acute kidney injury (AKI) risk secondary to significant gastrointestinal fluid losses Increased heart rate , a recognised class effect of GLP-1 receptor agonists Pancreatitis a potential risk that warrants prompt medical assessment if severe abdominal pain develops Thyroid C-cell tumours observed in rodent studies with GLP-1 receptor agonists
Eur J Pharm Sci
(2020) Growth Hormone Secretagogues: History, Mechanism of Action, and Clinical Development JCSM Rapid Communications
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