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The transcriptome reveals the molecular regulatory network of primordial follicle depletion in obese mice

JD: Conceptualization, Supervision, Validation, Writing original draft, Writing review & editing

Genetic mutations and metabolic factors like the depletion of glutathione in the system, which increases drug sensitivities, may have some hereditary predispositions as well

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Macrophage activation and foam cell formation may explain the elevated CRP serum levels and contribute to disease progression (Figure 9)