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Although severe complications are rare, working with a qualified and experienced provider is crucial

In advanced atherosclerosis stages, prostaglandin endoperoxide synthase 2 (PTGS2), ACSL4, caspase-1, and NOD-like receptor protein 3 (NLRP3) expression is upregulated, while GPX4 is downregulated

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5,6 Mosaicplasty, typically osteochondral autologous transplantation (OATs), is an open procedure where osteochondral plugs are harvested from non-weight bearing areas and transferred into the defect