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IL-6 is a molecule that is typically associated with immune responses and appears to be elevated during inflammation, potentially contributing to various inflammatory skin conditions

Mol Cell Biochem 395(12):110

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Regarding the motor activity change of the 5xFAD mouse, both hyper- (Spangenberg and Wichman, 2018), the Switchmaze test (Xeni et al., 2024) or vision depended behavior ( TABLE 3 Common changes related to NPS between AD patients and AD mouse models