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First, it is an endogenous molecule: it circulates in human plasma at a concentration of roughly 200 ng/mL around age 20, declining to about 80 ng/mL by age 60, a fall that has been linked, at least associatively, to the general decline in tissue regenerative capacity with age

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As depicted in Figure 6, our findings demonstrated a significant downregulation in the expression levels of TNF- and IL-1 upon treatment with GO@GSH-FA