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As an upstream event of ferroptosis, autophagy activation can induce ferroptosis through different mechanisms, including NCOA4-mediated ferritin autophagy [95], RAB7A-mediated lipid autophagy [96], ARNTL-mediated biological clock protein autophagy [97], and BECN1-mediated System X c inhibition [64]

Menghoum N, Oriot P, Hermans MP

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These systems allow for more versatile activation mechanisms Fig

Cagrilintide is a synthetic, long-acting analog of human amylin (islet amyloid polypeptide) classified as a dual amylin and calcitonin receptor agonist (DACRA)