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Several practical unknowns compound this

[73] failed to perform an adequate meta-analysis due to the high risk of bias and differences in methodology between studies

Novo Nordisk's blockbuster obesity treatment Wegovy mimics a hormone called GLP-1 to tamp down appetite and regulate blood sugar, while Eli Lilly's own drug Zepbound targets both GLP-1 and another hormone called GIP

Research points to GLP-1 as having a role in entraining the circadian rhythm of insulin release in the pancreas

Lopata AL, Kleine-Tebbe J, Kamath SD (2016) Allergens and molecular diagnostics of shellfish allergy: Part 22 of the Series Molecular Allergology