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FIGURE 1 2 Materials and methods 2.1 Reagents Dextran sulfate sodium salt (DSS, MW 36,00050,000 Da, batch number 160110) was purchased from MP Biomedicals

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Type 1 is an autoimmune condition requiring insulin replacement, and GLP-1 medications do not address the underlying pancreatic beta-cell destruction

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Consequently, this results in events such as T-cell death, reduced cytokine production, T-cell destruction, and the development of tolerance to antigens, thereby allowing tumors to escape immune detection [109]