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NICE guidance (NG198) recommends specialist referral for severe acne or when first-line treatments have been ineffective

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Clinical studies have shown that without adequate protein intake, up to 40% of the weight lost on semaglutide can be lean muscle mass rather than fat

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Many trials were designed to explore cardiovascular safety or benefit using SGLT2i molecules, including empagliflozin, dapagliflozin, canagliflozin, and ertugliflozin, which greatly differ in their characteristics, including the number of participants, study duration, the inclusion of patients with HF or renal disease, HF characterized by reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF), and associated comorbidities or risk factors, clearly implying differences in the risk and rate of cardiovascular or renal events recorded during the investigations [2]