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Metabolic tests showed that abnormal glucose levels and insulin resistance developed in the livers of mice fed a keto diet to a greater extent than in mice fed a high fat diet

You should not take semaglutide or tirzepatide if you have: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN2) History of pancreatitis or gallbladder disease Severe kidney or liver disease Diabetic retinopathy (in some cases) Severe gastrointestinal disease Pregnancy or breastfeeding This is not a complete list of contraindications

This is why every medical professional, every pharmacy, and every manufacturer gives the same advice about expired semaglutide

Freezing can cause the protein structure to unfold and clump together, which makes the medication ineffective