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Mechanisms of chronic central neuropathic pain after spinal cord injury

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They account for approximately one million lower-limb amputations each year, representing up to 85% of all diabetes-related amputations worldwide 7

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As such, the elevated abundance of microbes in the GM of IF-P participants observed in this study in tandem with the co-occurrence of metabolites indicative of protein degradation and mobilization and oxidation of fatty acids, such as methylmalonic acid, malonic acid, and succinate, presents a nascent multi-omic signature of IF-P