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The Difference Between Semaglutide and Tirzepatide Tirzepatide (Mounjaro) and Semaglutide (Ozempic, Wegovy) are both medications used to manage type 2 diabetes, but they differ in their mechanisms of action, compositions, and some other characteristics

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Specifically, rodent studies showed an increased incidence of thyroid C-cell tumours (medullary thyroid carcinoma) when exposed to GLP-1 receptor agonists at doses significantly higher than those used therapeutically in humans

If you suspect an adverse reaction to your medication, you can report it via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or through the Yellow Card app