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Gastrointestinal side effects of high-dose GLP-1 RAs and co-agonists occurred in 30%-70% of patients, mostly arising within the first 2 weeks of the first dose, being mild or moderate in severity, and transient [28]

This approach is particularly important in obesity medication, as research is progressing rapidly and new medications continue to enter clinical practice

Basal glucose levels in blood samples obtained from tail vein were determined by GlucoCard DIA meter (Arkray, Tokyo, Japan)

Paik KH, Choe YH, Park WH, Oh YJ, Kim AH, Chu SH, et al

Medical guidance is needed to avoid dosing errors, manage missed-dose timing, and monitor for changes in blood sugar and blood pressure