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[DOI] [PubMed] [Google Scholar] Tyring SGottlieb APapp KGordon KLeonardi CWang ALalla DWoolley MJahreis AZitnik R, et al

Mannick JB, Del Giudice G, Lattanzi M, Valiante NM, Praestgaard J, Huang B, Lonetto MA, Maecker HT, Kovarik J, Carson S, Glass DJ, Klickstein LB

First: PI3K/Akt/mTOR, which drives protein synthesis, glucose uptake (via GLUT4 translocation), and anti-apoptotic signaling (particularly relevant in muscle and neuronal tissue)

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This can cause thinning of the blood, which can lead to increased bleeding and other more serious problems