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The -phe1 substitution in both exendin and lixisenatide configurations displayed favourable characteristics including reduced internalisation and fast recycling, which translated to improved insulin secretion in vitro and significantly better anti-hyperglycaemic effect in vivo

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Dosing calculations: Determine daily dose based on protocol (typically 200-500mcg BPC-157, 2-5mg TB-500 twice weekly)

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Davis JF, Schurdak JD, Magrisso IJ, Mul JD, Grayson BE, Pfluger PT, et al

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There is no human clinical data establishing a timeline for gut-specific effects

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