The reason: since the fragment contains only the C-terminal part, it lacks the binding domains for GHR (most of the affinity of hGH for GHR lies in the central part of the molecule)
Contraindications Vitamin B12 injection is contraindicated in pregnant and lactating women, liver disease, kidney disease, infection, iron deficiency, folic acid deficiency, the patient undergoing treatment that has a direct effect on bone marrow, an allergy to medication, vitamin, preservative or cobalt
However, estrogen receptor -positive (ER+) breast cancers and androgen receptor-positive prostate cancer may adapt to hormone deprivation and acquire resistance to antiestrogen or antiandrogen therapies
10.1242/jeb.221606 [DOI] [PubMed] [Google Scholar] 13.Bratic A, Larsson NG
Banach, M