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In the CT-like conformation, the bypass motif becomes unstructured, and residues (S21-P28) are not well resolved, suggesting this flexible segment is exposed to the solvent environment
However, the inhibition of -GCS activity by GSH is of physiological significance [7] and is the rate-limiting step in GSH biosynthesis
Assessment and nutraceutical management of stress-induced adrenal dysfunction. Integrative Medicine 7.5 (2008): 18-25
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