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Either option works, but taking it in the morning on an empty stomach allows it to enter your system faster and may help you burn more fat

10.1002/ange.201712027 41 LingX.TuJ.WangJ.ShajiiA.KongN.FengC.et al (2019)

While glutathione is not a hormone and does not directly affect hormone production or regulation, it can indirectly affect hormone balance by reducing oxidative stress and inflammation, which are factors that can contribute to hormonal imbalances

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Dietary supplements containing beta carotene can also cause orange urine