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A diferencia de los mono y dual agonistas, semaglutida y tirzepatida, la retatrutida introduce el triple agonismo al dirigirse simultneamente a los receptores del pptido similar al glucagn-1 ( GLP-1 ), del polipptido insulinotrpico dependiente de glucosa ( GIP ) y, de manera crucial, al receptor de glucagn (GCGR)

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