Compared with people starting topiramate, those starting GLP-1 drugs were 48% less likely to start valproate, 42% less likely to start calcitonin gene-related peptide (CGRP) monoclonal antibodies, 35% less likely to start tricyclic antidepressants, and 23% less likely to start the class of drugs called gepants
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However, based on the populations studied in clinical trials to date, researchers have focused primarily on adults living with obesity typically defined as a body mass index (BMI) of 30 kg/m or above as well as those with overweight accompanied by at least one weight-related health condition, such as type 2 diabetes, hypertension, or dyslipidaemia
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Its important to note that these injections are not a magic bullet for weight loss and should be used in conjunction with other healthy lifestyle changes