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doi: 10.3389/fimmu.2025.1625087 Received 08 May 2025 Accepted 09 September 2025 Published 26 September 2025 Volume 16 - 2025 Edited by Ricieri Mocelin, Universidade Federal da Fronteira Sul, Brazil Reviewed by Ana Pamela Gmez-Garca, National Institute of Cancerology (INCAN), Mexico Ikbal Andrian Malau, China Medical University Hospital, Taiwan Updates Copyright 2025 Ge, Hu, Kan, Li, Xu, Zhang, Zheng, Wang and Du