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We generated human brain organoids and cultivated them for 100-day-old to allow maturation of neuronal cells (Fig

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Mitochondrial superoxide anion can react with nitric oxide (NO) generating the reactive radical peroxynitrite (ONOO - ) and both superoxide anion and ONOO - formation in mitochondria are important events contributing to APAP-induced hepatotoxicity (Ramachandran and Jaeschke, 2017)