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Castro-Marrero J, Domingo JC, Cordobilla B, et al

At Perfect B, we see this consistently: patients in their 30s and 40s with Fitzpatrick III-IV skin types who are eating well, training regularly, and still dealing with energy deficits, slower skin recovery, and body composition that does not track with their effort

Among the most discussed peptides in 2026 are MOTS-c and BPC-157

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This makes it more vulnerable to: Collagen loss (leading to wrinkles) Fluid retention (causing puffiness) Pigmentation changes (causing dark circles) Even small lifestyle changes like sleeping late or working under constant stress can make a big difference in how this area looks