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Essential role for premature senescence of myofibroblasts in myocardial fibrosis
10.1016/0361-9230(84)90190-4 112 WiseR
Adding to the discussion, a 2025 study from the University of Michigan, presented at the Endocrine Societys annual meeting, found that obese mice treated with tirzepatide lost about 20% of their body weight and developed significantly smaller breast tumors than control mice
What can we conclude To date, we have not seen robust reports that persons with obesity or overweight taking GLP-1 medications experience greater SMM loss than persons with obesity or overweight taking non-GLP-1 medications (after controlling for greater total weight loss)
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