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they undergo rapid metabolic inactivation following oral administration, and high doses may induce pro-oxidative effects

BSO-treated cells had a normal appearance with no apparent cell death, as observed by brightfield microscopy (Fig

Sturgeon C, Lan J, Fasano A

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In summary, Chinese medicine (Chinese herbal formulas, Chinese patent medicine, compounds and extracts from Chinese herbs) may play a role in the treatment of DN by inhibiting the production of ROS, alleviating oxidative stress and inflammatory responses, restoring mitochondrial function, and decreasing apoptosis, thereby reducing proteinuria, improving renal function, and decreasing renal pathological damage