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These words get mixed up constantly, but they describe different goals and methods: Lightening or whitening usually means reducing overall melanin production across large areas of skin, often with stronger agents that can carry higher risks of irritation, rebound pigmentation, or uneven results

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Sulforaphane treatment also led to suppression of key colorectal cancer stem cell markers, such as CD44 and CD133 in HCT116 and SW480 spheroids, facilitated by the TAp63 /Lgr5/ -catenin pathway (Wang et al., 2021)