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The temperature during the formation of the emulsion is not especially critical but in some cases, influences the size and quality of the microspheres and the solubility of the drug in the continuous phase

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[DOI] [PMC free article] [PubMed] [Google Scholar] 37.LEITCH HA, BUCKSTEIN R, ZHU N, et al

This targeted fat reduction happens because the medication changes lipid metabolism in white and brown adipose tissues, which leads to better fat burning