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On the basis of results of the most recent CVOTs (DAPA-HF, DAPA-CKD, EMPEROR-R), the FDA has approved dapagliflozin (2020) and empagliflozin (2021) to reduce risk for CV death and HF hospitalization in adults with HF and reduced ejection fraction regardless of whether they have diabetes [24, 25]
It also depends on the type of food you eat, the amount of physical activity you get each day, whether youre getting quality sleep and even stress and genetics
The end-use device is a metered-dose nasal spray pump