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Some osteogenic markers (e.g., ALP, RUNX2, OSX and COL-I) are secreted during the early stage of osteo/odontoblastic differentiation, whereas OCN is involved in the late-stage differentiation process 30,31,32,33

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An unfortunate thing I see is that patients, likely in large part due to the high stigma around weight gain, will not get in touch when they stop or are unable to continue the medications, Huang explains

Maintaining results in the full sense therefore requires a protocol that addresses all four dimensions not the number on a scale alone

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