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This reflects that device performance can change as the formulation degrades or interacts with container-closure materials over time

Referral to specialist servicesurology (for structural penile disease, Peyronie's disease, or refractory ED), endocrinology (for confirmed hypogonadism), cardiology (for symptoms or high cardiovascular risk), or psychosexual medicinemay be appropriate

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It can be prescribed to adults with obesity who have a body mass index (BMI) of 30 or above, or who are overweight with a BMI between 27 and 30 and at least one weight-related comorbidity, and should be used alongside a reduced-calorie diet and increased physical activity