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These direct comparisons allowed a more sensitive differentiation of HR effects, and confirmed that lixisenatide induces a significantly smaller increase in mean 24-h HR compared with liraglutide (4 vs

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(c) in warfarin rats (warfarin given intragastrically (1.5 mg/kg) once daily for 3 consecutive days, with the last challenge was at 3 hours before the bleeding procedure)

GLP-1 medications slow gastric emptying and alter appetite signaling, which can indirectly affect bile flow and lipid metabolism

B.et al (2006)