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Collective data from major clinical trials have shown that treatment with a DPP-4i improves glycemic control by increasing insulin secretion from islet cells, lowering levels of HbA1c, reducing adipocyte size, and suppressing inflammation [4751]

If a patient is considered an appropriate candidate, phentermine is started at a clinically appropriate dose with close supervision

When you are in a calorie deficit, your protein needs actually go up to protect your lean tissue

Fat-soluble vitamins and other hard-to-solubilize ingredients behave differently in water-based systems, and getting them into stable, effective, clean-label products takes more than standard emulsification

The mean reduction in body weight at 48 weeks was 24.2% in the 12-mg group the largest reduction observed to date in a Phase 2 trial of an anti-obesity medication. Jastreboff et al., New England Journal of Medicine, 2023 The Liver-Fat Result Beyond weight loss, retatrutide produced a result that surprised researchers: dramatic reductions in liver fat