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2 Granulomatous reactions to aluminum salts have been reported, and while these reactions can result in persistent pruritic nodules, this is considered a benign reaction that is self-resolving

A few structural facts from that review explain why reconstitution and storage instructions exist at all: Gastric stability: BPC-157's N-terminal polyproline cluster forms a rigid, protease-resistant structure, which is why it remains detectable in human gastric juice even after prolonged exposure to pepsin and stomach acid the physiological basis researchers cite for studying an oral (capsule) form at all

REGEN is supplied as lyophilized (freeze-dried) powder in sterile vials containing 10 mg total peptide content (5 mg BPC-157 + 5 mg TB-500)