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Melatonin is truly a pleiotropic hormone: beyond circadian rhythm regulation and sleep, it has notable antioxidant, immunological, and neuroprotective effects all of which have implications for age-related degeneration

[DOI] [PubMed] [Google Scholar] 189.Castle N.A

It is also worth paying attention to immunosuppressive medicines

The safety of luteolin can only be predicted from its enrollment in numerous clinical trials with different pathological conditions (ClinicalTrials.gov ID NCT06047899, ClinicalTrials.gov ID NCT05204407)

However, it's important to note that for pernicious anaemia or deficiency with neurological involvement, intramuscular hydroxocobalamin injections remain the first-line treatment in the UK, as recommended by NICE and the British Society for Haematology