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They likely reflect the difference between pathological IGF-1 excess (which does appear to increase cancer risk and accelerate ageing in some models) and normalisation of IGF-1 in individuals whose levels have declined below an optimal physiological range due to somatopause
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Promotes Heart Health: Helps lower triglycerides and improves circulation, reducing the risk of heart disease
Treatment with tirzepatide in adults with pre-diabetes and obesity or overweight resulted in sustained weight loss, and nearly 99% remained diabetes-free at 176 weeks | Eli Lilly and Company
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