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Common Side Effects Some of the most commonly reported side effects of tirzepatide in clinical trials are: Nausea and diarrhoea (which were reported to occur while the tirzepatide dose was increased) Decreased appetite Vomiting Constipation Indigestion Stomach Pain Tirzapetide may cause serious side effects in a few cases

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But many GLP-1 patients have moderate laxity that is not enough to justify surgery and not mild enough to ignore

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Current guidelines recommend an HbA1c goal of 300 to 5,000 mg/g), b 79.1% of patients had a left ventricular ejection fraction of 300 mg/g) in patients with micro-albuminuria, e Composite outcome of doubling of serum creatinine, end-stage renal disease, renal or cardiovascular death, f Composite outcome of cardiovascular death, hospitalization due to heart failure, and urgent visit due to heart failure