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For example: Certain antibiotics (such as chloramphenicol) may reduce the effectiveness of B12 therapy

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For a medication where precise dosing determines outcomes, that gap matters enormously

Interestingly, low blood levels of vitamin B12 have been linked with reduced bone mass, though clinical trials have not definitively supported the efficacy of B vitamin supplements in treating fractures ( Recent research states that the role of vitamin B12 and bone health is not well established

This offers a degree of precision that can be very advantageous in a research setting