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Our group demonstrated that PNPLA3 is a novel binding partner of ABHD5 in BAT, functioning to compete with PNPLA2 for binding to ABHD5, thereby inhibiting adipocyte lipolysis (70)

NF-B was found to be hyperactivated during aging, which impairs the generation of induced pluripotent stem cells, as there is a repression of NF-B during the reprogramming process of stem cells towards a pluripotent state [117]

Early observations came from gastric studies, then attention spread to soft tissue under mechanical stress

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