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Keywords: Pharmacokinetics, semaglutide, curve plasma concentrations, type 2 diabetes, obesity, glucagon-like peptide-1, drugdrug interaction Introduction Type 2 diabetes (T2D) and obesity are major public health burdens with an important economic impact and their incidences have increased in the past decades

There is some good evidence also that in people who have cardiovascular risk factors, in other words, people who are either susceptible

P., Pratley, R., Dagogo-Jack, S., et al

The combination of both drugs with a balanced diet, regular exercise, and other lifestyle changes produces the best results

References: MHRA GDP/Orange Guide (temperature excursion expectations)