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Tiano JP, Mauvais-Jarvis F (2012) Importance of oestrogen receptors to preserve functional -cell mass in diabetes

P.ParmenterB.A.-O

This M1 polarization leads to increased expression of pro-inflammatory markers (such as CD80 and CD86) and cytokines (like IL-1, IL-6, and IL-12), while reducing levels of immunosuppressive cytokines such as IL-10

18-22 GLP-1 RAs also induce a significant reduction in body weight through delayed gastric emptying and promotion of satiety, which has led to their study in weight management

Research suggests it influences growth factor expression, particularly VEGF and EGF, which play crucial roles in tissue regeneration