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In the process of glucose oxidation, NADP + is reduced to NADPH (reduced NAD phosphate)

10.1210/en.2012-1294 Endocrinology 32 CascorbiI.DrakoulisN.BrockmollerJ.MaurerA.SperlingK.RootsI

And when these fat cells produce elevated levels of the hormone, that can lead to chronic inflammation, which is a major contributing factor for breast cancer