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The melanotic macules are usually brown, deep blue/black, or black, and they are well circumscribed with sharp, delineated borders

Vitamin B12 1mg/2ml Injection Philo Composition: **Active Ingredient:** Cyanocobalamin (Vitamin B12) - 1 mg per 2 mL **Excipients:** Sodium Chloride (for isotonicity) Water for Injection Hydrochloric Acid (for pH adjustment) Sodium Hydroxide (for pH adjustment) #### Dosage: **Adults:** **Initial Dose:** 1 mg (1 mL) intramuscularly or subcutaneously, administered once daily for 1 week

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Nat Rev Cancer (2010) 10(12):8717

In comparison, the average cup of coffee contains 95 mg of caffeine, so this isn't considered a large amount unless you're especially sensitive to the effects of caffeine