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Semaglutide a GLP-1 receptor agonist is already well established in UK practice for type 2 diabetes mellitus in the form of Ozempic and Wegovy for obesity, both manufactured by Novo Nordisk

With fewer compound pharmacies likely filling the need due to the shortage being lifted, patients and healthcare providers might experience a tightening in supply availability

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This likely occurs through suppression of appetite via central mechanisms and increased satiety secondary to suppression of gastric emptying, via inhibition of peristalsis of the stomach while simultaneously increasing tonic contraction of the pyloric region

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