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For the erosion index, six sites in the ankle joint were scored: the talus, navicular bone, medial cuneiform bone, and the bases of the first, second, and third metatarsals

Common side effects during the first 2-4 weeks include mild nausea, reduced appetite for certain foods, and occasional constipation or diarrhea

These include metformin, which can be used alongside GLP-1 medications (see our guide on taking metformin and tirzepatide together ), as well as naltrexone and bupropion

Now, 48 days in, Ive lost 70 pounds

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