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They also reduced catabolic enzyme activity and promoted anabolic matrix formation, consistent with the anti-catabolic and anabolic actions described in preclinical OA models

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Conducted in artificial cell lines, the findings did not address the key question as to whether the truncated form of GLP-1 located in the gut activated the pancreas to release insulin in the way incretin was presumed to work

[DOI] [PMC free article] [PubMed] [Google Scholar] Li H, Han W, Villar VA, Keever LB, Lu Q, Hopfer U, Quinn MT, Felder RA, Jose PA, Yu P (2009) D1-like receptors regulate NADPH oxidase activity and subunit expression in lipid raft microdomains of renal proximal tubule cells